Mankone Ntsaba is a Management Consultant and runs her own company, Tsinde Development Consultants. She is a Trustee and Deputy Chair of Kagiso Trust and serves as a member of the Boards of Kagiso Tiso Holdings, Lepelle Northern Water and RISIMA Housing Finance Corporation, a subsidiary of the Limpopo Economic Development Agency.
She spent more than ten years as a researcher and consultant at the CSIR. She is also a management training facilitator at the National School of Government. She has previously served as a member of the Ministerial Advisory Council at the then Department of Water Affairs and Forestry (DWAF). She has contributed to the establishment of several NGOs and CBOs whose purpose was to facilitate access to economic empowerment opportunities in rural areas. She is a member of the Institute of Directors (IoDSA) and The Ethics Institute (TEI).