Mankone Ntsaba is a management consultant and runs her own company, Tsinde Development Consultants. She is a Trustee of KT and serves as a member of the Boards of Kagiso Trust and RISIMA Housing Finance Corporation.
She spent a number of years as a researcher and consultant at the CSIR. She is also a management training facilitator at the National School of Government. She was a member of the Ministerial Advisory Council at the then Department of Water Affairs and Forestry (DWAF). She has contributed to the establishment of a number of NGOs and CBOs whose purpose was to facilitate access to economic empowerment opportunities in rural areas. She is a member of the Institute of Directors (IoDSA).